Journal of the American Geriatrics Society
Gregory M. Ouellet, John R. O'Leary, Christopher G. Leggett, Jonathan Skinner, Mary E. Tinetti, Andrew B. Cohen
Although the potential benefits of anticoagulation for AF diminish as individuals with dementia develop more profound cognitive and functional loss, guidelines currently provide little guidance about when to consider discontinuation. This study provides valuable information to clinicians and surrogate decision-makers as they discuss whether to continue anticoagulation in patients with advanced dementia, who have high dementia-related mortality and for whom the primary goal is most frequently comfort.